Frequently Asked Questions Regarding Michigan’s New e-Prescribing Requirement - Michigan State Medical Society
Michigan has implemented a new e-prescribing requirement for controlled substances, effective June 1, 2025. All prescriptions for Schedule II-V controlled substances must be electronically prescribed, with limited exceptions.
Aforeworn detected this change in the Pharmacy & Controlled Substances space on July 28, 2026 and published this briefing so affected operators are forewarned rather than caught off guard. It is rated High urgency. All Michigan prescribers and pharmacies dispensing controlled substances should confirm how it applies to their specific situation before acting. There is a time constraint attached: June 1, 2025. Acting after that point can mean penalties, a lapsed licence, or lost eligibility — exactly the kind of surprise Aforeworn exists to prevent. Aforeworn monitors Pharmacy & Controlled Substances continuously and turns every detected change into a plain-English briefing like this one, so you always know first. Forewarned is forearmed.
What changed
Michigan now mandates e-prescribing for all controlled substances (Schedules II-V), replacing previous allowances for paper or oral prescriptions.
Who it affects
All Michigan prescribers and pharmacies dispensing controlled substances
What you must do
Ensure your electronic health record (EHR) or pharmacy system supports e-prescribing for controlled substances and that all prescribers are enrolled in the Michigan Prescription Drug Monitoring Program (PDMP).
Deadline
June 1, 2025
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