A Aforeworn
Forewarned is forearmed.
Home › Niches › Cannabis & Hemp Operators › Change
Low urgency

Ordering Schedule I and II Controlled Substances Using DEA Form 222; Technical Amendments

Detected July 30, 2026 · in Cannabis & Hemp Operators

DEA updates Form 222 to a single-sheet format for ordering Schedule I and II controlled substances; technical amendments effective immediately.

Aforeworn detected this change in the Cannabis & Hemp Operators space on July 30, 2026 and published this briefing so affected operators are forewarned rather than caught off guard. It is rated Low urgency. DEA registrants authorized to order Schedule I and II controlled substances, including cannabis researchers and manufacturers handling controlled substances. should confirm how it applies to their specific situation before acting. There is a time constraint attached: Effective immediately upon publication (March 20, 2026).. Acting after that point can mean penalties, a lapsed licence, or lost eligibility — exactly the kind of surprise Aforeworn exists to prevent. Aforeworn monitors Cannabis & Hemp Operators continuously and turns every detected change into a plain-English briefing like this one, so you always know first. Forewarned is forearmed.

What changed

The DEA final rule changes the format of Form 222 from a triplicate to a single-sheet form; technical amendments only, no substantive changes to ordering procedures.

Who it affects

DEA registrants authorized to order Schedule I and II controlled substances, including cannabis researchers and manufacturers handling controlled substances.

What you must do

Use the new single-sheet Form 222 for all orders of Schedule I and II controlled substances; discard old triplicate forms.

Deadline

Effective immediately upon publication (March 20, 2026).

Source: https://www.federalregister.gov/documents/2026/03/20/2026-05482/ordering-schedule-i-and-ii-controlled-substances-using-dea-form-222-technical-amendments

Never miss a change like this again

Aforeworn watches Cannabis & Hemp Operators around the clock and alerts you the moment a rule moves — with a plain-English brief on what to do.

Start your free trial

Related changes in Cannabis & Hemp Operators