High urgency

Schedules of Controlled Substances: Placement of MDMB-4en-PINACA in Schedule I

Detected July 16, 2026 · in Pharmacy & Controlled Substances

DEA places MDMB-4en-PINACA into Schedule I, making it illegal to possess, handle, or dispense without DEA registration.

Aforeworn detected this change in the Pharmacy & Controlled Substances space on July 16, 2026 and published this briefing so affected operators are forewarned rather than caught off guard. It is rated High urgency. All pharmacies handling controlled substances should confirm how it applies to their specific situation before acting. There is a time constraint attached: Effective immediately upon publication (April 24, 2026).. Acting after that point can mean penalties, a lapsed licence, or lost eligibility — exactly the kind of surprise Aforeworn exists to prevent. Aforeworn monitors Pharmacy & Controlled Substances continuously and turns every detected change into a plain-English briefing like this one, so you always know first. Forewarned is forearmed.

What changed

MDMB-4en-PINACA is now a Schedule I controlled substance with no accepted medical use.

Who it affects

All pharmacies handling controlled substances

What you must do

Immediately cease any possession, dispensing, or compounding of MDMB-4en-PINACA; secure and dispose of any existing inventory per DEA regulations.

Deadline

Effective immediately upon publication (April 24, 2026).

Source: https://www.federalregister.gov/documents/2026/04/24/2026-08104/schedules-of-controlled-substances-placement-of-mdmb-4en-pinaca-in-schedule-i

Never miss a change like this again

Aforeworn watches Pharmacy & Controlled Substances around the clock and alerts you the moment a rule moves — with a plain-English brief on what to do.

Start your free trial

Related changes in Pharmacy & Controlled Substances