Schedules of Controlled Substances: Temporary Placement of 5,6- Dichloro Brorphine, 5,6-Dichloro Desmethylchlorphine, N-Propionitrile Chlorphine, and Spirochlorphine in Schedule I of the Controlled Substances Act
DEA temporarily places four synthetic opioids (5,6-Dichloro Brorphine, 5,6-Dichloro Desmethylchlorphine, N-Propionitrile Chlorphine, and Spirochlorphine) into Schedule I, making them illegal to possess, manufacture, or distribute.
Aforeworn detected this change in the Pharmacy & Controlled Substances space on July 16, 2026 and published this briefing so affected operators are forewarned rather than caught off guard. It is rated High urgency. All pharmacies, especially independent, retail chains, compounding, and long-term-care pharmacies should confirm how it applies to their specific situation before acting. There is a time constraint attached: Immediately upon publication (July 1, 2026); no grace period.. Acting after that point can mean penalties, a lapsed licence, or lost eligibility — exactly the kind of surprise Aforeworn exists to prevent. Aforeworn monitors Pharmacy & Controlled Substances continuously and turns every detected change into a plain-English briefing like this one, so you always know first. Forewarned is forearmed.
What changed
Four new substances are now Schedule I controlled substances, subject to all federal prohibitions and penalties.
Who it affects
All pharmacies, especially independent, retail chains, compounding, and long-term-care pharmacies
What you must do
Immediately cease any possession, dispensing, or distribution of these substances; update internal controlled substance lists and PDMP systems; notify staff.
Deadline
Immediately upon publication (July 1, 2026); no grace period.
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